Detalhe da pesquisa
1.
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.
Cell
; 184(5): 1281-1298.e26, 2021 03 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33592174
2.
Silent mutations reveal therapeutic vulnerability in RAS Q61 cancers.
Nature
; 603(7900): 335-342, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35236983
3.
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs.
Nature
; 575(7781): 229-233, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31666694
4.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature
; 569(7757): 503-508, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31068700
5.
Acute pharmacological degradation of Helios destabilizes regulatory T cells.
Nat Chem Biol
; 17(6): 711-717, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34035522
6.
Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours.
Br J Cancer
; 126(7): 1027-1036, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34887522
7.
Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC.
Bioorg Med Chem Lett
; 68: 128718, 2022 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35378251
8.
Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response.
Proc Natl Acad Sci U S A
; 116(3): 1027-1032, 2019 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30598450
9.
Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).
Br J Cancer
; 125(4): 582-592, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34088988
10.
Effects of the multi-kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia.
J Cell Mol Med
; 24(5): 2968-2980, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31967735
11.
The combination of FLT3 and SYK kinase inhibitors is toxic to leukaemia cells with CBL mutations.
J Cell Mol Med
; 24(3): 2145-2156, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31943762
12.
Comparison of effects of midostaurin, crenolanib, quizartinib, gilteritinib, sorafenib and BLU-285 on oncogenic mutants of KIT, CBL and FLT3 in haematological malignancies.
Br J Haematol
; 187(4): 488-501, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31309543
13.
Inhibition of USP10 induces degradation of oncogenic FLT3.
Nat Chem Biol
; 13(12): 1207-1215, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-28967922
14.
Prevalence and Therapeutic Targeting of High-Level ERBB2 Amplification in NSCLC.
J Thorac Oncol
; 19(5): 732-748, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38154514
15.
TREX1 Inactivation Unleashes Cancer Cell STING-Interferon Signaling and Promotes Antitumor Immunity.
Cancer Discov
; 14(5): 752-765, 2024 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38227896
16.
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin.
Commun Biol
; 7(1): 426, 2024 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38589567
17.
Cotargeting a MYC/eIF4A-survival axis improves the efficacy of KRAS inhibitors in lung cancer.
J Clin Invest
; 133(16)2023 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37384411
18.
Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma.
bioRxiv
; 2023 Nov 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37961132
19.
The BRD4-NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma.
Cancer Res
; 83(23): 3846-3860, 2023 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37819236
20.
Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma.
Clin Cancer Res
; 29(24): 5128-5139, 2023 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37773632